Purposes of the Research Project

Plasma consists of a variety of reactive species(ions, electrons, radicals and emitting photons).In discharge plasmas, these reactive species aregenerated via ionization and dissociation ofgaseous molecules through collisions withaccelerated electrons. Due to enhanced reactivityof these reactive species, plasma has beenemployed as major tools for material processesincluding formations of ultrafine structures andfunctional layers, which are indispensable as keymanufacturing technology for advanced industriesand eventually have taken a role as coretechnology to support the state-of-the-artadvancement of scientific frontiers.

Meanwhile, in the last decade, technologicalprogress has been made to generate non-thermallow-temperature plasma in atmospheric-pressuregas and in liquid, in which the gas temperature ismaintained at a room temperature. Recently thenon-thermal plasmas have been applied tomedical treatments, in which remarkable effectshave been found in apoptotic behaviors of cancercells, skin-disease therapy and wound healing,and thus the plasma is expected to bringsignificant innovations in medical science andtechnologies.

The goal of our research project is to create“Plasma Medical Innovation” as a novel academicfield for development of innovative technologies inmedical treatments through establishment ofscientific basis involved in plasma interactionswith biomolecules, cells and living bodies. Inparticular, our research project is to place specialemphasis on studies and systematization of theinteractions based on “plasma science” and“molecular biology”.

Contents of the Research Project

For creation of the field “Plasma MedicalInnovation” and leading the worldwide researchactivities, it is of key significance to establishfollowing schemes to evolve the novel academicfield via utilizing unique scientific achievementsgained in the “advanced plasma-process science”,which has lead the industries worldwide, fordevelopment of medical science and molecularbiology.

  1. Development of unique plasma sources anddiagnostic technologies through establishmentof methodologies to study the interactions basedon plasma science.
  2. To study the interactions on the atomic and themolecular scales based on molecular biology fortheoretical systematization.
  3. Evolution of the novel academic field viasystematic research activities that coverinteraction studies and experiments on animals,evaluation of side effects (toxicity), andestablishment of international guidelines toassure safety as medical treatments.

Systematization as the plasma medicalscience shall be attained via collaborative studiesin 1) and 2). Furthermore, innovative medicaltechnologies with novel plasma sources anddiagnostic systems shall be developed throughsystematic research activities via 3) together with1) and 2).

Expected Outcomes and ScientificSignificance

The achievement of our goal is expected tocontribute significantly to a) enhancement andpromotion of academic level of our nation andmoreover b) substantial promotion of “the lifeinnovation” through medical innovations andevolutions that are attained via development ofthe novel medical technologies alternative to theconventional ones.

Key Words

plasma medicine, molecular biology, plasmainteractions with living body, life innovation

Term of Project and Budget Allocation

FY2012-2016, 1,131,800,000 JPY


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