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研究成果

受賞歴 2013年8月(プラズマ医療国際イノベーションセンター設立)以降

  • 2017年3月1日 工学部 市川知範 電気学会東海支部長賞
  • 2017118 工学部 古田凌 講演奨励賞 第34回プラズマプロセシング研究会(SPP34)/29回プラズマ材料科学シンポジウム
  • 2015年9月 工学部 倉家 尚之 Student Award AEPSE 2015
  • 2014年5月26日  医学部  飯田真智子「若手優秀演題賞」 (第84回日本衛生学会学術総会)
  • 2014年4月19日  医学部  内海史「IS Award」 (第66回日本産科婦人科学会学術講演会)
  • 2014年2月7日   工学部 竹田圭吾, 8th International Conference on Reactive Plasmas 31st Symposium on Plasma Processing, ICRP-8 Young Award "Silver Medal"
  • 2014年1月17日 工学部   田中宏昌,「第8回わかしゃち奨励賞」優秀賞, 愛梨研若手研究者イノベーション創出奨励事業

研究成果 2013年8月(プラズマ医療国際イノベーションセンター設立)以降

  • N. Kurake, H. Tanaka, K. Ishikawa, K. Nakamura, H. Kajiyama, F. Kikkawa, M. Mizuno, Y. Ikehara, M. Hori, Crystallization of calcium oxalate dihydrate in a buffered calcium-containing glucose solution by irradiation with non-equilibrium atmospheric pressure plasma, J Appl Phys, 122 (2017) 143301.
  • R. Furuta, N. Kurake, K. Ishikawa, K. Takeda, H. Hashizume, H. Tanaka, H. Kondo, M. Sekine, M. Hori, Intracellular responses to reactive oxygen and nitrogen species, and lipid peroxidation in apoptotic cells cultivated in plasma-activated medium, Plasma Process. Polym., (2017) 6.
  • R. Furuta, N. Kurake, K. Takeda, K. Ishikawa, T. Ohta, M. Ito, H. Hashizume, H. Tanaka, H. Kondo, M. Sekine, M. Hori, Lipid droplets exhaustion with caspases activation in HeLa cells cultured in plasma-activated medium observed by multiplex coherent anti-Stokes Raman scattering microscopy, Biointerphases, 12 (2017) 031006.
  • K. Nakamura, Y. Peng, F. Utsumi, H. Tanaka, M. Mizuno, S. Toyokuni, M. Hori, F. Kikkawa, H. Kajiyama, Novel Intraperitoneal Treatment With Non-Thermal Plasma-Activated Medium Inhibits Metastatic Potential of Ovarian Cancer Cells, Sci Rep, 7 (2017) 6085.
  • H. Tanaka, K. Ishikawa, M. Mizuno, S. Toyokuni, H. Kajiyama, F. Kikkawa, H.R. Metelmann, M. Hori, State of the art in medical applications using non-thermal atmospheric pressure plasma, Rev. Mod. Plasma Phys. , 1 (2017) 1: 3.
  • L. Shi, F. Ito, Y. Wang, Y. Okazaki, H. Tanaka, M. Mizuno, M. Hori, T. Hirayama, H. Nagasawa, D.R. Richardson, S. Toyokuni, Non-thermal plasma induces a stress response in mesothelioma cells resulting in increased endocytosis, lysosome biogenesis and autophagy, Free radical biology & medicine, 108 (2017) 904-917.
  • N. Wada, J.I. Ikeda, H. Tanaka, H. Sakakita, M. Hori, Y. Ikehara, E. Morii, Effect of plasma-activated medium on the decrease of tumorigenic population in lymphoma, Pathology, research and practice, 213 (2017) 773-777.
  • Takeda Keigo, Ishikawa Kenji, Tanaka Hiromasa, Sekine Makoto, H. Masaru, Spatial distributions of O, N, NO, OH and vacuum ultraviolet light along gas flow direction in an AC-excited atmospheric pressure Ar plasma jet generated in open air, Journal of Physics D: Applied Physics, 50 (2017) 195202.
  • N. Kurake, H. Tanaka, K. Ishikawa, K. Takeda, H. Hashizume, K. Nakamura, H. Kajiyama, T. Kondo, F. Kikkawa, M. Mizuno, M. Hori, Effects of •OH and •NO radicals in the aqueous phase on H2O2 and NO2- generated in plasma-activated medium, J Phys D Appl Phys, 50 (2017) 155202.
  • Takeda Keigo, Kumakura Takumi, Ishikawa Kenji, Tanaka Hiromasa, Sekine Makoto, H. Masaru, Behavior of absolute densities of atomic oxygen in the gas phase near an object surface in an AC-excited atmospheric pressure He plasma jet, Appl Phys Express, 9 (2017) 036201.
  • H. Tanaka, M. Hori, Medical applications of non-thermal atmospheric pressure plasma, J Clin Biochem Nutr, 60 (2017) 29-32.
  • H. Kajiyama, F. Utsumi, K. Nakamura, H. Tanaka, S. Toyokuni, M. Hori, F. Kikkawa, Future perspective of strategic non-thermal plasma therapy for cancer treatment, J Clin Biochem Nutr, 60 (2017) 33-38.
  • S. Takeda, S. Yamada, N. Hattori, K. Nakamura, H. Tanaka, H. Kajiyama, M. Kanda, D. Kobayashi, C. Tanaka, T. Fujii, M. Fujiwara, M. Mizuno, M. Hori, Y. Kodera, Intraperitoneal Administration of Plasma-Activated Medium: Proposal of a Novel Treatment Option for Peritoneal Metastasis From Gastric Cancer, Annals of surgical oncology, (2017).
  • H. Tanaka, K. Nakamura, M. Mizuno, K. Ishikawa, K. Takeda, H. Kajiyama, F. Utsumi, F. Kikkawa, M. Hori, Non-thermal atmospheric pressure plasma activates lactate in Ringer's solution for anti-tumor effects, Sci Rep, 6 (2016) 36282.
  • H. Tanaka, M. Mizuno, F. Kikkawa, M. Hori, Interactions between a Plasma-activated medium and Cancer Cells, Plasma Medicine, 6 (2016) 101-106.
  • R. Matsumoto, K. Shimizu, T. Nagashima, H. Tanaka, M. Mizuno, F. Kikkawa, M. Hori, H. Honda, Plasma-Activated Medium Selectively Eliminates Undifferentiated Human Induced Pluripotent Stem Cells, Regenerative Therapy, 5 (2016) 55-63.
  • N. Kurake, H. Tanaka, K. Ishikawa, K. Nakamura, H. Kajiyama, F. Kikkawa, M. Mizuno, Y. Yamanishi, M. Hori, Synthesis of calcium oxalate crystals in culture medium irradiated
    with non-equilibrium atmospheric-pressure plasma, Appl Phys Express, 9 (2016) 1-4.
  • C. Ishida, M. Mori, K. Nakamura, H. Tanaka, M. Mizuno, M. Hori, A. Iwase, F. Kikkawa, S. Toyokuni, Non-thermal plasma prevents progression of endometriosis in mice, Free Radical Res, (2016) 1-9.
  • H. Kajiyama, F. Utsumi, K. Nakamura, H. Tanaka, M. Mizuno, S. Toyokuni, M. Hori, F. Kikkawa, Possible therapeutic option of aqueous plasma for refractory ovarian cancer, Clinical Plasma Medicine, 4 (2016) 14-18.
  • T. Ito, K. Ishikawa, D. Onoshima, N. Kihara, K. Tatsukoshi, H. Odaka, H. Hashizume, H. Tanaka, H. Yukawa, K. Takeda, H. Kondo, M. Sekine, Y. Baba, M. Hor, Microfluidic Transport Through Microsized Holes Treated by Nonequilibrium Atmospheric-Pressure Plasma, Ieee T Plasma Sci, PP (2016) 1-6.
  • F. Utsumi, H. Kajiyama, K. Nakamura, H. Tanaka, M. Mizuno, S. Toyokuni, M. Hori, F. Kikkawa, Variable susceptibility of ovarian cancer cells to non-thermal plasma-activated medium, Oncology reports, 35 (2016) 3169-3177.
  • L. Shi, Y. Wang, F. Ito, Y. Okazaki, H. Tanaka, M. Mizuno, M. Hori, D.R. Richardson, S. Toyokuni, Biphasic effects of l-ascorbate on the tumoricidal activity of non-thermal plasma against malignant mesothelioma cells, Archives of biochemistry and biophysics, 605 (2016) 109-116.
  • N. Kurake, H. Tanaka, K. Ishikawa, T. Kondo, M. Sekine, K. Nakamura, H. Kajiyama, F. Kikkawa, M. Mizuno, M. Hori, Cell survival of glioblastoma grown in medium containing hydrogen peroxide and/or nitrite, or in plasma-activated medium, Archives of biochemistry and biophysics, 605 (2016) 102-108.
  • H. Tanaka, M. Mizuno, K. Ishikawa, H. Kondo, K. Takeda, H. Hashizume, K. Nakamura, F. Utsumi, H. Kajiyama, H. Kano, Y. Okazaki, S. Toyokuni, S. Akiyama, S. Maruyama, S. Yamada, Y. Kodera, H. Kaneko, H. Terasaki, H. Hara, T. Adachi, M. Iida, I. Yajima, M. Kato, F. Kikkawa, M. Hori, Plasma with high electron density and plasma-activated medium for cancer treatment, Clinical Plasma Medicine, 3 (2015) 72-76.
  • H. Tanaka, M. Mizuno, S. Toyokuni, S. Maruyama, Y. Kodera, H. Terasaki, T. Adachi, M. Kato, F. Kikkawa, M. Hori, Cancer therapy using non-thermal atmospheric pressure plasma with ultra-high electron density, Phys Plasmas, 22 (2015) 122003.
  • N. Hattori, S. Yamada, K. Torii, S. Takeda, K. Nakamura, H. Tanaka, H. Kajiyama, M. Kanda, T. Fujii, G. Nakayama, H. Sugimoto, M. Koike, S. Nomoto, M. Fujiwara, M. Mizuno, M. Hori, Y. Kodera, Effectiveness of plasma treatment on pancreatic cancer cells, International journal of oncology, 47 (2015) 1655-1662.
  • F.X. Ye, H. Kaneko, Y. Nagasaka, R. Ijima, K. Nakamura, M. Nagaya, K. Takayama, H. Kajiyama, T. Senga, H. Tanaka, M. Mizuno, F. Kikkawa, M. Hori, H. Terasaki, Plasma-activated medium suppresses choroidal neovascularization in mice: a new therapeutic concept for age-related macular degeneration, Sci Rep, 5 (2015).
  • F. Utsumi, H. Kajiyama, K. Nakamura, H. Tanaka, M. Hori, F. Kikkawa, Selective cytotoxicity of indirect nonequilibrium atmospheric pressure plasma against ovarian clear-cell carcinoma, SpringerPlus, 3 (2014) 398.
  • K. Torii, S. Yamada, K. Nakamura, H. Tanaka, H. Kajiyama, K. Tanahashi, N. Iwata, M. Kanda, D. Kobayashi, C. Tanaka, T. Fujii, G. Nakayama, M. Koike, H. Sugimoto, S. Nomoto, A. Natsume, M. Fujiwara, M. Mizuno, M. Hori, H. Saya, Y. Kodera, Effectiveness of plasma treatment on gastric cancer cells, Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association, 18 (2014) 635-643.
  • H. Tanaka, M. Mizuno, K. Ishikawa, K. Takeda, K. Nakamura, F. Utsumi, H. Kajiyama, H. Kano, Y. Okazaki, S. Toyokuni, S. Maruyama, F. Kikkawa, M. Hori, Plasma Medical Science for Cancer Therapy: Toward Cancer Therapy Using Nonthermal Atmospheric Pressure Plasma, Ieee T Plasma Sci, 42 (2014) 3760-3764.
  • H. Tanaka, M. Mizuno, K. Ishikawa, K. Nakamura, F. Utsumi, H. Kajiyama, H. Kano, S. Maruyama, F. Kikkawa, M. Hori, Cell survival and proliferation signaling pathways are downregulated by plasma-activated medium in glioblastoma brain tumor cells, Plasma Medicine, 2 (2014) 207-220.
  • Y. Okazaki, Y. Wang, H. Tanaka, M. Mizuno, K. Nakamura, H. Kajiyama, H. Kano, K. Uchida, F. Kikkawa, M. Hori, S. Toyokuni, Direct exposure of non-equilibrium atmospheric pressure plasma confers simultaneous oxidative and ultraviolet modifications in biomolecules, J Clin Biochem Nutr, 55 (2014) 207-215.
  • H. Kajiyama, K. Nakamura, F. Utsumi, H. Tanaka, M. Hori, F. Kikkawa, Perspective of strategic plasma therapy in patients with epithelial ovarian cancer: A short
    review of plasma in cancer treatment, Jpn J Appl Phys 1, 53 (2014) 1-4.
  • T. Adachi, H. Tanaka, S. Nonomura, H. Hara, S.I. Kondo, M. Hori, Plasma-activated medium induces A549 cell injury via a spiral apoptotic cascade involving the mitochondrial-nuclear network, Free radical biology & medicine, 79C (2014) 28-44.
  • F. Utsumi, H. Kajiyama, K. Nakamura, H. Tanaka, M. Mizuno, K. Ishikawa, H. Kondo, H. Kano, M. Hori, F. Kikkawa, Effect of Indirect Nonequilibrium Atmospheric Pressure Plasma on Anti-Proliferative Activity against Chronic Chemo-Resistant Ovarian Cancer Cells In Vitro and In Vivo, Plos One, 8 (2013) e81576.
  • H. Tanaka, M. Mizuno, K. Ishikawa, K. Nakamura, F. Utsumi, H. Kajiyama, H. Kano, S. Maruyama, F. Kikkawa, M. Hori, Cell survival and proliferation signaling pathways are downregulated by plasma-activated medium in glioblastoma brain tumor cells, Plasma Medicine, 2 (2014) 207-220.

参考 2013年8月(プラズマ医療国際イノベーションセンター設立)以前

  • H. Tanaka, M. Mizuno, K. Ishikawa, K. Nakamura, H. Kajiyama, H. Kano, F. Kikkawa, M. Hori, Plasma-Activated Medium Selectively Kills Glioblastoma Brain Tumor Cells by Down-Regulating a Survival Signaling Molecule, AKT Kinase, Plasma Medicine, 1 (2013) 265-277.
  • S. Iseki, K. Nakamura, M. Hayashi, H. Tanaka, H. Kondo, H. Kajiyama, H. Kano, F. Kikkawa, M. Hori, Selective killing of ovarian cancer cells through induction of apoptosis by nonequilibrium atmospheric pressure plasma, Appl Phys Lett, 100 (2012) 113702.
     

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